Botox vs. Dysport vs. Xeomin vs. Jeuveau vs. Daxxify vs. Letybo
Botox vs. Dysport vs. Xeomin vs. Jeuveau vs. Daxxify vs. Letybo: Which Neuromodulator Is Right for You?
If you're considering Botox or another wrinkle-smoothing treatment, you've probably realized there are a lot of options. From Botox to Dysport to Jeuveau, Xeomin, Daxxify, and even the newer Letybo, it can get confusing fast.
So, how do you choose?
In this guide, we'll break down each neuromodulator, how they work, how long they last, and what makes them different—in simple, easy-to-understand terms.
How Do Botox and Other Neuromodulators Work?
All of these treatments are botulinum toxin-based injectables that temporarily relax facial muscles to smooth out wrinkles. They work by blocking signals between your nerves and muscles, preventing them from over-contracting.
The result? Softer, smoother skin and fewer expression lines.
These treatments are commonly used for:
✅ Forehead lines
✅ Crow’s feet (around the eyes)
✅ Frown lines (between the eyebrows, aka the “11s”)
✅ Bunny lines (on the nose)
✅ Lip flip (subtle lip enhancement)
✅ Jawline slimming and TMJ relief
Now, let’s compare the different types of tox!
1. Botox: The Classic Choice
Brand Name: Botox® (OnabotulinumtoxinA)
⏳ Onset: 3-5 days
⏳ Duration: 3-4 months
💡 Why people love it:
The most well-known and widely used wrinkle relaxer
Precise, predictable results
FDA-approved for multiple cosmetic and medical uses
📌 Best for: Anyone looking for a tried-and-true wrinkle treatment with a solid track record.
2. Dysport: The Fast-Acting Option
Brand Name: Dysport® (AbobotulinumtoxinA)
⏳ Onset: 2-3 days (faster than Botox)
⏳ Duration: 3-4 months
💡 Why people love it:
Works faster than Botox (great for last-minute events!)
Spreads more, which can be ideal for larger treatment areas like the forehead
📌 Best for: People who want fast results or need a softer, more natural spread for larger areas.
3. Xeomin: The “Clean” Toxin
Brand Name: Xeomin® (IncobotulinumtoxinA)
⏳ Onset: 3-4 days
⏳ Duration: 3-4 months
💡 Why people love it:
No added proteins (reduces the risk of resistance over time)
Some believe it gives a more natural look
📌 Best for: Those concerned about long-term resistance or who prefer a "purer" formulation.
4. Jeuveau: The Botox Alternative
Brand Name: Jeuveau® (PrabotulinumtoxinA)
⏳ Onset: 3-4 days
⏳ Duration: 3-4 months
💡 Why people love it:
Marketed as the “Newtox”—a newer, fresher alternative to Botox
Designed exclusively for aesthetic use (no medical applications)
📌 Best for: Those looking for a Botox alternative at a potentially lower price point.
5. Daxxify: The Longest-Lasting Neurotoxin
Brand Name: Daxxify® (DaxxibotulinumtoxinA)
⏳ Onset: 1-2 days (one of the fastest!)
⏳ Duration: 6-9 months (much longer than Botox!)
💡 Why people love it:
Lasts up to twice as long as Botox, meaning fewer injections per year
Uses a peptide stabilizer instead of human or animal-based proteins
📌 Best for: People who want longer-lasting results and fewer trips to the injector’s office.
6. Letybo: The Newest Player in the U.S.
Brand Name: Letybo® (LetibotulinumtoxinA)
⏳ Onset: 3-5 days
⏳ Duration: 3-4 months
💡 Why people love it:
A newer botulinum toxin on the U.S. market
Comparable to Botox in onset and duration
📌 Best for: Those who like to try the latest innovations in the beauty industry.
Comparison Chart: Botox vs. Dysport vs. Xeomin vs. Jeuveau vs. Daxxify vs. Letybo
So, Which Neurotoxin Is Right for You?
Want the classic, proven option? → Botox
Need quick results? → Dysport
Worried about resistance? → Xeomin
Looking for a Botox alternative? → Jeuveau
Want longer-lasting effects? → Daxxify
Excited about new treatments? → Letybo
At the end of the day, the best choice depends on your goals, anatomy, and injector’s recommendation.
If you're still unsure, schedule a consultation with Sara Courtney, nurse practitioner, to discuss your options!
Frequently Asked Questions (FAQ)
🔹 Does Botox last longer than Dysport?
No, they last about the same (3-4 months), but Dysport kicks in slightly faster. Duration of Botox varies based on dosing and individual patient response.
🔹 Is Daxxify better than Botox?
Not necessarily—Daxxify lasts longer, but Botox has a longer history of use.
🔹 Which is the best neurotoxin for beginners?
Botox is a great starting point, but your injector will help you decide what’s best for your face & goals.
Final Thoughts
Choosing the right neurotoxin doesn’t have to be overwhelming. By understanding how they work, how long they last, and their differences, you can make an informed decision.
Still have questions? Book a consultation and get expert advice tailored to you!
